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Updated: Jul 12, 2025

Looking for Driver Pathways of Acquired Resistance to Targeted Therapy: Drug Resistant Subclone Generation and Sensitivity Restoring by Gene Knock-down
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揭示内分泌治疗耐药HER2+/ER+乳腺癌的脆弱性

Shaymaa Bahnassy1, Hillary Stires2, Lu Jin1

  • 1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA.

Endocrinology
|October 28, 2023
PubMed
概括

对内分泌疗法耐药HER2+/ER+乳腺癌的新模型揭示了脆弱性. 将GPX4抑制剂与抗HER2药物的结合显示出治疗这种具有挑战性的乳腺癌亚型的前景.

关键词:
在HER2+/ER+中.乳腺癌 乳腺癌 乳腺癌内分泌耐药性的内分泌抵抗.人类表皮生长因子受体2

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