老年人和年轻成年人急性严重性结肠炎的管理和结果的差异
Taylor Boyd1,2, Elizabeth Bonareri Araka2, Bharati Kochar1,2
1Harvard Medical School, Harvard University, Boston, MA, USA.
Journal of Crohn's & colitis
|October 28, 2023
概括
与年轻患者相比,患有性结肠炎的老年人接受的医疗救援治疗较少,并在一年内接受紧急手术和死亡率较高. 需要进一步的研究,以优化对这一脆弱群体的护理.
科学领域:
- 胃肠病学 胃肠病学
- 老年医学 老年医学
- 临床医学 临床医学
背景情况:
- 与年轻人相比,患有性结肠炎的老年人患病率更高.
- 严重的UC住院对老年人群构成独特的挑战.
研究的目的:
- 调查老年 (≥65岁) 和年轻的患者之间治疗和治疗结果的差异,这些患者住院时患有严重UC.
- 为了比较医疗和手术救援疗法,术后并发症,虚弱和死亡率.
主要方法:
- 对因急性严重UC而住院的患者进行回顾性队列研究,需要静脉注射类固醇.
- 65岁以上的成年人和年轻的成年人 (14-64岁) 之间的结果比较.
主要成果:
- 老年人接受医疗救援治疗的可能性是50% (OR 0.45,95% CI 0.22-0.91),特别是最脆弱的人.
- 老年患者的紧急/紧急手术率较高 (50%vs13%),住院后虚弱度增加 (33%至42%).
- 近三分之一的老年人在一年内死亡,UC或其并发症导致了这些死亡的半数.
结论:
- 患有严重UC的老年人减少了医疗救援治疗的使用,增加了紧急手术率,以及更高的1年死亡率.
- 对于患有严重UC的住院老年人来说,护理和结果存在显著的差异.
- 优化老年UC患者的护理途径至关重要.
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