在急诊室,多佩里多尔减轻了胃衰竭症状 (DRUGS)
Natalie Stirrup1, Gavin Jones2, Jason Arthur3
1Department of Pharmacy and Therapeutics, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Slot # 571, Little Rock, AR 72205, United States of America.
The American journal of emergency medicine
|October 28, 2023
概括
德罗佩里多尔有效地减少了急诊室患者的阿片类药物和抗药的使用. 这种治疗可以改善疼痛控制,但不会影响住院时间或住院率.
科学领域:
- 胃肠病学 胃肠病学
- 紧急医疗 紧急医疗
- 药理学 药理学是指药理学的学科.
背景情况:
- 胃衰竭是一种慢性疾病,其特征是胃排空延迟.
- 它经常导致急诊室 (ED) 访问和住院.
- 对于胃衰竭症状的有效治疗选择仍然有限.
研究的目的:
- 评估多佩里多尔对ED中胃衰竭患者阿片类药物治疗的影响.
- 评估德罗佩里多尔对缓解症状,包括控制疼痛的影响.
- 为了确定德罗佩里多尔对抗嘔吐药的使用,住院时间和住院率的影响.
主要方法:
- 对233名胃衰竭患者进行了回顾性分析,这些患者呈现ED.
- 治疗用德罗皮多尔的患者与没有服用德罗皮多尔的患者之间的结果比较.
- 评估阿片类药物治疗,疼痛评分,抗使用,停留时间和成本.
主要成果:
- 德罗佩里多尔的使用显著降低了对阿片类药物治疗的需求 (46%对60%,P=0.0040).
- 接受德罗佩里多尔治疗的患者报告疼痛量表减少4分,抗药使用减少 (60%vs73%,P=0.0045).
- 在ED或住院时间,入院率或费用方面没有发现显著差异.
结论:
- 德罗佩里多尔有效地减少了ED中胃衰竭患者的阿片类药物和抗药需求.
- 它提供了显著的疼痛缓解,而不会对逗留时间或入院率产生不利影响.
- 德罗佩里多尔是一种有价值的治疗选择,用于管理胃衰竭恶化.
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