左心房应变预测了密码性中风患者中风复发和死亡的情况
Alberto Vera1, Alberto Cecconi1, Álvaro Ximénez-Carrillo2
1Cardiology Department, La Princesa University Hospital, Autonomous University of Madrid, IIS-IP, CIBER-CV, Madrid, Spain.
The American journal of cardiology
|October 28, 2023
概括
左心房应变储存器 (LASr) 预测了脑卒中复发或密码性脑卒中 (CS) 后的死亡. 较低的LASr值表明风险更高,有助于识别需要密切监测血栓栓塞的患者.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 医疗成像医学成像
背景情况:
- 左心房应变 (LAS) 被研究用于预测心房动 (AF) 后密码性中风 (CS).
- 在CS患者中,LAS对中风复发和死亡的预后作用不太清楚.
- 识别高风险的CS患者对于及时干预至关重要.
研究的目的:
- 调查LAS在CS患者中中风复发或死亡的预后价值.
- 为了确定 LAS 参数是否可以识别 CS 后具有更高不良结果风险的患者.
主要方法:
- 预计招募92名患有缺血性中风/TIA和ABCD2评分≥4.4的患者.
- 心声图包括入院期间的LAS评估.
- 随访时间平均为28个月,以记录中风复发或死亡的复合结果.
主要成果:
- 主要结局发生在16%的患者中.
- 在具有主要结局的患者中观察到下部LAS水库 (LASr) 和LAS导管 (LAScd).
- 多变量分析确定了LASr (HR 0.9,p=0.048) 和糖尿病 (HR 3.3,p=0.045) 作为中风复发或死亡的预测因素.
结论:
- 下部LAS水库与中风复发或中风后死亡的风险增加有关.
- LAS参数可能有助于识别CS患者有更高的血栓栓塞和压力风险.
- 进一步的研究可以完善LAS在CS风险分层中的使用.
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