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Updated: Jul 12, 2025

Author Spotlight: Characterizing DNA G-Quadruplex by Bis-3-Chloropiperidine Based Chemical Mapping
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作为新的DNase I抑制剂的替代二甲酸:合成,结构特征,体外评估和分子对接研究

Nina Ruseva1, Mariyana Atanasova1, Hristina Sbirkova-Dimitrova2

  • 1Department of Chemistry, Faculty of Pharmacy, Medical University of Sofia, 2 Dunav Str., 1000, Sofia, Bulgaria.

Chemico-biological interactions
|October 28, 2023
PubMed
概括

合成了两种新的替代二甲酸盐,并对它们对脱氧核糖核酶I (DNase I) 的抑制作用进行了评估. 化合物3a表现出强大的DNase I抑制,没有观察到细胞毒性,表明潜在的治疗应用.

关键词:
抑制DNase I的抑制作用对接研究对接研究广场上的朋友们.在XO抑制中,XO抑制抑制.

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