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Updated: Jul 12, 2025

Quantitative Methods to Study Protein Arginine Methyltransferase 1-9 Activity in Cells
08:11

Quantitative Methods to Study Protein Arginine Methyltransferase 1-9 Activity in Cells

Published on: August 7, 2021

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m6A甲基转移酶METTL3通过促进TRAF6依赖的线粒体ROS生产,促进了后心脏病发作后的交感性过活性

Peijin Yang1, Yu Wang2, Weili Ge3

  • 1Department of Cardiology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Medicine and Health Key Laboratory of Cardiac Electrophysiology and Arrhythmia, Jinan, China; Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.

Free radical biology & medicine
|October 28, 2023
PubMed
概括

甲基转移酶类酶3 (METTL3) 通过调节对心肌梗塞 (MI) 后的m6A修饰来促进交感性过活和心律失常. 抑制METTL3可以降低氧化应激,改善心脏功能.

关键词:
在METTL3中,METTL3是METTL3的第一个类型.心肌梗塞的心脏病发作这是一个PVN,PVN.交感性多动症 (Sympathetic hyperactivity) 是一种表现出同情心的多动症.在TRAF6/ECSIT路径中.m6A 一个很好的.

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