杏仁体和前额叶皮层之间的功能连接是处理情绪模两可的基础
Sai Sun1,2, Hongbo Yu3, Rongjun Yu4
1Frontier Research Institute for Interdisciplinary Sciences, Tohoku University 6-3 Aramaki aza Aoba, Aoba-ku, Sendai, 980-8578, Japan. sun.sai.e2@tohoku.ac.jp.
Translational psychiatry
|October 29, 2023
概括
这项研究揭示了大脑如何使用多式联络分析处理模两可的面部情绪. 它确定了关键的大脑区域及其涉及理解和解决情绪模两可的连接.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 情感科学是一种情感科学.
背景情况:
- 面部情绪处理依赖于分布式大脑网络.
- 判断模两可的情绪表达需要多区域大脑协调.
研究的目的:
- 了解面部表情中感知模糊性的神经机制.
- 通过多式联网功能连接分析实现网络层面的理解.
主要方法:
- 多模式功能连接分析.
- 在神经外科患者中直接进行神经元记录.
- 电脑图 (EEG) 连贯性和源连接性分析.
主要成果:
- 在杏仁体,dorsomedial前额叶皮层 (dmPFC) 和ventromedial前额叶皮层 (vmPFC) 之间发现了方向有效连接.
- 杏仁体和dmPFC的神经反应由情绪模糊性调节,杏仁体反应较早.
- 在编码情绪模两可中涉及的围膜-额头连贯性和三角形-α交叉频率合.
- EEG源连接表示dmPFC行使了自上而下的调节.
结论:
- 涉及杏仁体-PFC连接的神经网络是情绪模糊性处理的基础.
- 无论是自下而上的还是自上而下的流程,都对解决模糊性至关重要.
- 杏仁体-PFC连接的功能障碍可能与神经精神病患者的改变行为反应有关.
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