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Updated: Jul 12, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
06:54

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells

Published on: October 27, 2020

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由TGFβ激活的圆形RNA通过增强IGF2BP3介导的PDPN mRNA稳定性来促进瘤转移

Ke Li1, Jiawei Guo1, Yue Ming1

  • 1Laboratory of Molecular Oncology, Frontiers Science Center for Disease-related Molecular Network, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.

Nature communications
|October 29, 2023
PubMed
概括

这项研究确定circITGB6,一个TGFβ诱导的循环RNA,作为表皮细胞-介质细胞过渡 (EMT) 和癌症转移的关键驱动因素. 向circITGB6显示出抑制结直肠癌 (CRC) 传播的希望.

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Published on: June 23, 2023

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Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs10:32

Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs

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