在不孕症护理中非常早放弃的负担:全国性基于人口的队列研究
Khaoula Ben Messaoud1,2, Jean Bouyer1,2, Juliette Guibert3
1Institut National d'Etudes Démographiques, Ined, Sexual and Reproductive Health and Rights Unit-UR14, Aubervilliers, France.
Human reproduction (Oxford, England)
|October 29, 2023
概括
尽管有免费的不育治疗,但22%的女性在克洛米芬酸盐 (CC) /淋巴激素循环失败后提前退出. 低于贫困线的患者更有可能停止护理,突出非财务障碍.
科学领域:
- 生殖医学 生殖医学
- 医疗保健服务研究 医疗服务研究
- 卫生社会学 卫生社会学
背景情况:
- 在不孕症护理中,高退学率显著影响治疗成功.
- 之前的研究主要集中在IVF/ICSI中断,通常归因于财务障碍.
- 克洛米芬酸盐 (CC) /淋巴激素治疗后影响学的因素需要特别调查.
研究的目的:
- 为了确定不成功的CC / 淋巴腺激素治疗后非常早期断课的频率.
- 识别非常早期退学的相关因素,特别是在完全覆盖成本的背景下.
- 了解不孕不育治疗延续的差异.
主要方法:
- 一个全国性的基于人口的队列研究,使用法国医疗保险和医院数据库.
- 包括27,416名年龄在18-49岁的妇女,在2017年接受了不成功的CC / 淋巴激素治疗.
- 使用多变量逻辑回归分析非常早期的断药 (在1-3个月内停止治疗).
主要成果:
- 22%的妇女经历了CC/淋巴激素治疗失败后的非常早期放弃.
- 较高的学率与年轻 (<25岁) 和年长 (≥35岁) 的年龄相关,低于贫困线,全科医生的CC处方,以及缺乏不孕测试.
- 低于贫困线的患者表现出显著更高的早期学风险,尽管完全覆盖了成本.
结论:
- 非财务障碍在很大程度上导致不孕不育护理的早期退学,即使成本已支付.
- 社会经济地位,年龄和全科医生的治疗管理是与学相关的关键因素.
- 建议加强从业人员培训,以应对各种患者需求并减少治疗差异.
相关概念视频
Infertility in Females
326
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
Endometriosis, a condition characterized by abnormal growth of...
326
Infertility in Males
276
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
276
In Vitro Fertilization
305
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
305
Meiosis II
183.5K
Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each...
183.5K
Kidney Transplant III: Nursing Management
22
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
22
Oogenesis
63.8K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
63.8K


