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肠道移植后的异常性阴道
Elsadig Hussan1, Alexander Kroemer1,2, Ahmed M Elsabbagh3
1MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC.
Transplantation direct
|October 30, 2023
概括
在肠道移植 (ITx) 后,异常性乳腺是常见的,但不会影响移植的存活率. 风险包括结肠直肠切除术,结肠缺乏,以及免疫因素.
科学领域:
- 胃肠病学 胃肠病学
- 移植手术 移植手术
- 免疫学 免疫学 免疫学
背景情况:
- 在肠道移植 (ITx) 后的异常性乳腺发病很少被讨论.
- 它的自然历史和与移植拒绝的关联仍然不清楚.
研究的目的:
- 为了回顾ITx后异常性阴茎的经验.
- 识别风险因素,了解这种病理的临床过程.
主要方法:
- 在217名患者中对225个ITx进行了回顾性审查,其中至少有1年的移植存活时间.
- 常规移植内镜和考克斯回归分析,以评估随时间推移的发病风险.
主要成果:
- 41%的患者发病了;50人在90天内 (与患者年龄和循环结肠形成有关),43人在90天后 (与移植结肠的缺失有关).
- 需要延长治疗的与新型捐赠体特异性抗体和NOD突变有关.
- 并没有与移植的拒绝或失败有关.
结论:
- 在ITx后的异常性相对较为常见.
- 风险因素包括结肠静脉结构,无结肠移植和免疫因素.
- 这种情况对移植结果的独立影响最小.
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