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新生儿重症监护病房中的菌感染:一项回顾性观察性研究
Gaffari Tunc1, Arife Toksoz2, Fatih Kilicbay3
1Department of Pediatrics, Division of Neonatology, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Türkiye.
概括
过早出生婴儿的真菌败血症与长时间的机械通风和全方位肠道营养有关. 减少住院时间和实施查可以降低新生儿重症监护室 (NICU) 的真菌败血症率.
科学领域:
- 新生儿科学 新生儿科学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 性败血症对新生儿重症监护室 (NICU) 的婴儿构成重大威胁.
- 了解风险因素和结果对于有效管理至关重要.
研究的目的:
- 评估性败血症婴儿的人口特征,危险因素,死亡率和实验室发现.
- 为了比较患有*Candida albicans*和*Candida non-albicans*感染的婴儿之间的结果.
主要方法:
- 对患有*Candida* spp. 的NICU患者进行了回顾性多中心研究. 在血液培养中 (2019年11月 - 2022年9月).
- 患者被分为第一组 (*C. albicans*) 和第二组 (*C. non-albicans*).
主要成果:
- 在3450名NICU婴儿中,有1.6%患有*Candida*感染;57%的婴儿极度早产.
- 长时间的机械通风 (MV) 和全腹腔营养 (TPN) 在第二组更长.
- 由于真菌真菌病的死亡率为35%,其中65%具有并发症.
结论:
- 长时间的MV和TPN与真菌败血症发病率的增加有关.
- 建议缩短住院时间和实施有效的查计划,以减少NICU中的真菌败血症.
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