在头癌幸存者的晚期喉功能障碍
Sarah Almas1, Caroline C Jeffery1
1Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, Faculty of Medicine and Dentistry University of Alberta Edmonton Alberta Canada.
Laryngoscope investigative otolaryngology
|October 30, 2023
概括
晚期喉功能障碍在头癌幸存者中很常见,影响声音和吞. 这种功能障碍在治疗后几年出现静态,突出显示了幸存者面临的持续挑战.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 在瘤学瘤学.
- 语音和听力科学 语言和听力科学
背景情况:
- 头癌 (HNC) 幸存者面临着独特的挑战,喉功能障碍是严重的担忧,因为它对重要功能产生影响.
- 喉对于发声,吞和呼吸道保护至关重要,使其功能障碍成为HNC幸存者的主要致病源.
研究的目的:
- 在长期头癌幸存者的队列中描述晚期喉功能障碍的性质和患病率.
- 调查治疗后的时间与喉功能障碍的存在之间的相关性.
主要方法:
- 预期招募HNC幸存者至少2年治疗后.
- 收集视频鼻镜检查结果,视频光镜吞研究和临床结果评估.
- 描述性统计和因子分析,以探索临床变量和结果之间的相关性.
主要成果:
- 分析了30名幸存者 (平均年龄66岁,80%为男性),主要治疗口腔状细胞癌.
- 常见的症状包括吞功能障碍 (83%) 和语音变化 (67%).
- 在61%的参与者中观察到声运动异常 (VFMA),治疗后的时间和喉功能障碍之间没有显著的相关性.
结论:
- 晚期喉功能障碍是头癌幸存者的持续问题,有助于显著的发病率.
- 观察到的喉功能障碍似乎是静态的,在癌症治疗后数十年保持不变,这表明需要长期管理策略.
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