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影响乳腺甲状腺癌侧侧淋巴结转移的预测因素
Ozan Caliskan1, Mehmet Taner Unlu1, Ceylan Yanar2
1Division of Endocrine Surgery, Department of General Surgery, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.
Sisli Etfal Hastanesi tip bulteni
|October 30, 2023
概括
中枢淋巴结转移是乳头甲状腺癌中侧面淋巴结转移的独立危险因素. 这一发现支持考虑预防性中央部剖析和对乳头甲状腺癌患者的密切随访.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 头部和部手术 头部和部手术
背景情况:
- 在乳头甲状腺癌 (PTC) 中,侧侧淋巴结转移 (LLNM) 显著影响手术决策和患者预后.
- 识别LLNM的风险因素对于优化治疗策略至关重要.
研究的目的:
- 评估与PTC患者LLNM发展相关的临床病理风险因素.
- 确定在PTC中LLNM的独立预测因素.
主要方法:
- 从2012年5月至2020年9月期间手术的346名PTC患者的人口和临床病理数据的回顾性分析.
- 患者被分为具有LLNM和没有LLNM的组.
- 使用多变量分析来确定独立的风险因素.
主要成果:
- 在10.4%的PTC患者中观察到LLNM.
- 有关LLNM和没有LLNM的组之间的显著差异包括男性性别,较大的瘤大小,淋巴血管入侵,多中心性,多焦点性,攻击性变体,甲状腺外延伸和中枢淋巴结转移 (CLNM).
- 多变量分析确定CLNM是LLNM的一个独立风险因素.
结论:
- 中枢淋巴结转移是乳头甲状腺癌中侧侧淋巴结转移的重要独立预测因子.
- 在LLNM患者中,CLNM的高发病率表明应该考虑预防性中央部剖析.
- CLNM作为一个有价值的指标,用于手术程度和密切跟踪检测复发.
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