在COVID-19后住院患者的认知障碍和危险因素
Jedsada Khieukhajee1, Arada Rojana-Udomsart1, Pinnakarn Srisarakorn1
1Department of Neurology, Neurological Institute of Thailand, Bangkok, Thailand.
Dementia and geriatric cognitive disorders extra
|October 30, 2023
概括
后COVID-19认知障碍,或"大脑雾",影响超过60%的住院患者. 然而,多年的教育是唯一的预测因素,与健康个体相比,没有发现显著的认知差异.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 认知科学 认知科学
背景情况:
- 被称为"脑雾"的认知缺陷在2019年新冠病毒病 (COVID-19) 后经常被报告.
- 与COVID-19后认知障碍相关的临床特征和危险因素仍在争论中.
- 了解这些缺陷对于患者的管理和康复至关重要.
研究的目的:
- 为了确定COVID-19住院治疗后认知障碍的患病率.
- 描述在COVID-19后患者中观察到的认知缺陷的性质.
- 确定认知障碍的危险因素,并将认知功能与健康对照进行比较.
主要方法:
- 对34名住院患有SARS-CoV-2感染的患者进行了神经心理和临床评估.
- 在2周的随访中,使用TMSE和MoCA测试来评估认知功能.
- 一个由22名健康个体组成的比较小组被纳入认知功能评估.
主要成果:
- 观察到COVID-19后认知障碍的流行率为61.76% (MoCA分数<25).
- 多年的教育成为认知障碍的唯一预测因素.
- 多变量分析表明,在后急性COVID-19患者和健康对照者之间,认知结果没有统计学上显著的差异.
结论:
- 在COVID-19后住院治疗中,存在适度的认知功能障碍,这与先前的研究一致.
- 尽管报告了缺陷,但在将患者与健康个体进行比较时,没有发现显著的认知差异.
- 需要进行进一步的纵向研究,以确定SARS-CoV-2感染与认知功能障碍之间的因果关系.
相关概念视频
01:30Negative and Cognitive Symptoms of Schizophrenia
50
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
50
01:26Factors Affecting the Risk of Infection
11.9K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.9K
01:30Cognitive Development During Adulthood
125
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
125
01:20COPD: Pathogenesis and Clinical Features
305
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
305
01:30Pneumonia I: Introduction
248
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
248
01:29Pneumonia II: Pathophysiology
296
The pathophysiology of pneumonia involves the following steps:
296