外分胰腺衰竭可能与非典型的慢性移植对宿主疾病有关
Yuka Hosokawa1, Tomomi Toubai1, Koichi Ohya1
1Division of Hematology and Cell Therapy, Department of Internal Medicine III, Yamagata University Faculty of Medicine, Yamagata, Japan.
Case reports in oncology
|October 30, 2023
概括
一位骨髓移植患者经历了慢性腹和由于异位胰腺功能不充分而导致的体重减轻. 用胰腺酶治疗改善了症状,这表明与移植与宿主疾病 (GVHD) 有联系.
科学领域:
- 胃肠病学 胃肠病学
- 血液学 血液学 血液学
- 移植医学是一种移植医学.
背景情况:
- 移植与宿主疾病 (GVHD) 可以影响骨髓移植后的多个器官.
- 胃肠道 (GI) 症状的GVHD是常见的,但胰腺功能不充分不经常报告.
研究的目的:
- 报告一种可能由非典型的慢性GVHD引起的异位胰腺功能衰竭病例.
- 以突出诊断挑战和治疗结果在这种情况下.
主要方法:
- 一个66岁的女性患者在异构骨髓移植后的病例报告.
- 临床评估包括结肠镜检查,便检查,腹部CT扫描和胰腺酶水平评估.
- 用胰腺酶替代疗法进行治疗.
主要成果:
- 患者在移植后14个月出现持续性腹和体重减轻.
- 调查显示,胰腺缩,胰腺外分泌酶显著降低,但内分泌功能完好无损.
- 随着胰腺酶治疗,症状显著改善.
结论:
- 在骨髓移植后患有不明原因的外分胰腺功能衰竭的患者中,应考虑非典型的慢性GVHD.
- 胰腺酶替代疗法可以有效地管理GVHD诱导的胰腺功能不全的症状.
相关概念视频
01:24Chronic Pancreatitis I: Introduction
95
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
95
01:40Cell-mediated Immune Responses
68.6K
Overview
68.6K
01:29Chronic Pancreatitis II: Collaborative Care
96
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
96
01:27Acute Pancreatitis I: Introduction
380
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
380
01:30Acute Pancreatitis II: Clinical Manifestations and Management
131
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
131