在稳定的冠状动脉疾病患者中,在寒冷中急性上肢运动后,巴罗反射敏感性
Kalle Pikkarainen1, Rasmus I P Valtonen2, Heidi E Hintsala3
1Center for Environmental and Respiratory Health Research, Research Unit of Population Health, University of Oulu, Oulu, Finland.
Frontiers in physiology
|October 30, 2023
概括
寒冷的环境与运动相结合,对冠状动脉疾病患者的自主神经系统恢复的影响因运动类型而异. 静态运动在寒冷中增强恢复,而动态运动损害了它.
科学领域:
- 心血管生理学心血管生理学
- 自主神经系统的调节规则
- 环境运动生理学 运动生理学
背景情况:
- 寒冷的环境和运动独立地影响自主神经系统 (ANS),巴罗反射灵敏度 (BRS) 和血压变化 (BPV).
- 寒冷暴露和运动对冠状动脉疾病 (CAD) 患者运动后自主和心血管恢复的综合影响仍然基本未知.
- 了解这些相互作用对于解释心血管疾病患者对低环境温度的脆弱性至关重要.
研究的目的:
- 研究寒冷环境和身体上部运动 (静态和动态) 对稳定冠状动脉疾病 (CAD) 患者运动后自主和心血管恢复的联合影响.
- 为了比较在寒冷 (-15°C) 和中性 (+22°C) 环境中进行运动的反应.
主要方法:
- 一项交叉试验,涉及20名稳定的CAD患者,他们在寒冷和中性环境中进行了30分钟的静态和动态上肢运动.
- 持续的心电图和血压监测被用来计算心率 (HR),血压变化 (BPV) 和巴罗反射灵敏度 (BRS) 在运动后低频和高频的光谱功率.
- 测量是在运动停止后10分钟和30分钟进行的.
主要成果:
- 在寒冷的环境中静态的上肢运动导致心率 (HF RR) 的高频 (HF) 频谱功率增加,心率降低,与中性环境相比,低频/高频 (LF/HF) 比率更低.
- 运动后的BRS平均值和高频率的BRS在冷静运动后明显高于中性条件.
- 与中性环境相比,在寒冷中动态的上肢运动导致运动后HF BRS和缩血压降低.
结论:
- 在寒冷的环境中静态的上肢运动可以提高运动后的巴罗反射灵敏度和阴道活动,而不会对CAD患者的缩血压产生负面影响.
- 在寒冷的天气下动态上肢运动会损害运动后的阴道巴罗反射敏感性,但不会显著改变其他测量到的心血管参数.
- 需要进一步的研究,以充分阐明冷暴露对运动后自主和心血管反应的影响,特别是静态上肢运动后,以更好地了解心血管疾病患者对寒冷的脆弱性.
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