在提供皮肤穿术治疗恶性阻塞性尿路病的后续治疗时,其含义与泌尿器官恶性瘤的后续治疗:我们可以更有选择性吗?
Elizabeth Osinibi1, Hong Doan2, Alejandro Mercado-Campero3
1Darent Valley Hospital Medway Maritime Hospital, Darenth Wood Road, Dartford, DA2 8DA, UK.
Therapeutic advances in urology
|October 30, 2023
概括
针对恶性尿路阻塞的皮肤通术 (PN) 提供了很高的成功率,但影响生活质量而没有改善生存率. 仔细的患者选择和预后讨论对于这种干预至关重要.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 穿皮瘤切除术 (PN) 是对恶性尿道阻塞 (MUO) 的常见干预措施.
- 虽然成功,但PN与发病率有关,并没有改善整体存活率.
- 在MUO中调查PN结果为患者选择和咨询提供了信息.
研究的目的:
- 在患有恶性尿道阻塞的患者中评估皮肤通术的结果.
- 为了比较不同瘤手术服务可用性的医院之间的结果.
- 为患者咨询提供有关终身瘤切除术的预后和影响的信息.
主要方法:
- 从2015年1月到2018年12月的电子记录的回顾性审计.
- 包括经过PN的膀和前列腺癌患者.
- 两家英国医院之间不同瘤手术服务模式的结果比较.
主要成果:
- 261名患者接受了PN;78名患者患有前列腺或膀癌.
- 12个月死亡率在第1医院 (82%) 与第2医院 (52%) 相比显著更高.
- 平均存活时间因癌症组而异,单边PN和双边PN之间的死亡率没有显著差异.
结论:
- 大多数来自前列腺或膀癌的MUO患者在PN后的生存时间不到12个月.
- 终身 nefrostomy 的预后和影响需要与患者和家人进行仔细的讨论.
- 对于MUO的PN,需要仔细考虑疾病预后和患者选择.
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