相关实验视频

Updated: Jul 12, 2025

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
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An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

Published on: November 3, 2010

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基因调节表达对复杂特征的介导作用量化的稳定性与介导表达得分回归

Chen Lin1, Wei Liu2, Wei Jiang1

  • 1Department of Biostatistics, Yale University, New Haven, CT 06510, United States.

Biology methods & protocols
|October 30, 2023
PubMed
概括

介导表达分数回归 (MESC) 可能会低估遗传性,因为模型的错误规范. 基因注释错误导致低估,而SNP注释错误导致遗传关联研究中的高估.

关键词:
LDSC LDSC LDSC LDSC LDSC LDSC LDSC LDSC LDSC LDSC LDSC LDSC LDSC LDSC我们的eQTL是eQTL.基因调节表达的基因表达.通过介导的遗传性.

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