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抗素抗体识别了与类风湿性关节炎相关的T细胞表位,这些表位被细菌L-asparaginase修饰

Tsvetelina Batsalova1, Ivanka Teneva1, Krum Bardarov2

  • 1Faculty of Biology, Paisii Hilendarski University of Plovdiv, Plovdiv, Bulgaria.

Central-European journal of immunology
|October 30, 2023
PubMed
概括

细菌L-asparaginase修改了类风湿性关节炎 (RA) 患者的T细胞表观,导致交叉反应性抗蛋白抗体 (ACPAs) 识别特定的动机. 这种修改可能会将T细胞原始化与RA的自身抗体发育联系起来.

关键词:
在L-asparaginase的使用中.的T细胞表位.抗素蛋白抗体 (ACPAs) 是一种抗素蛋白抗体.病变的发生和发病.后翻译修改后的修改.类风湿性关节炎 类风湿性关节炎第二种类型的原.

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