通过175厘米的Truselect微导管输送状辅助树脂y90:高残留的案例因素,尽管双冲 протокол
Alan Alper Sag1, Ethan Agritelley2, James Ronald1
1Division of Vascular and Interventional Radiology, Department of Radiology, Duke University Medical Center, .
Nuclear medicine communications
|October 30, 2023
概括
这项研究使用SIROS和TruSelect微导管评估了-90 (Y90) 输送的效率,发现94%的输液残留活性低于10%. 这些发现突显了这种组合对Y90放射栓塞的有效性.
科学领域:
- 干预性放射学 干预性放射学
- 核医学就是核医学.
- 在瘤学瘤学.
背景情况:
- 选择性内部辐射疗法 (SIROS) 是一种正在发展中的肝癌治疗技术.
- 优化-90 (Y90) 输送对于有效的放射性栓塞至关重要.
- "TruSelect"微导管和双冲 протокол代表了Y90输送系统的进步.
研究的目的:
- 为了评估Y90 Sir-Spheres输送的效率,使用SIROS系统与175厘米TruSelect微导管和双冲 протокол.
- 为了确定处理后剩余Y90活性的百分比.
主要方法:
- 从2019年至2022年通过TruSelect微导管注射SIROS Y90 Sir-Spheres的患者的回顾性评估.
- 分析计划,交付和剩余的Y90活动.
- 评估影响残留活动的因素,包括SIROS预校准,肝体积和动脉静止.
主要成果:
- 在11种癌症类型的25名患者中分析了48次输液.
- 平均Y90残留活性为4.9%±2.8%,其中94%的输液残留量为<10%.
- 与较高的残留活性相关的因素包括3天SIROS,活性<10mCi,较小的肝体积和记录的动脉静止.
结论:
- 结合SIROS,TruSelect微导管和双冲 протокол,在Y90输送中实现了高效率,大多数情况下残留活性<10%.
- 需要进行进一步的研究,以探索基于高残留剂量的预测因子的剂量测量和剂量准备的微导管特定考虑因素.
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