临床和成像参数与急性失偿心力衰竭患者的功能障碍相关,减少排泄分数
In-Jeong Cho1, Sang-Eun Lee2, Dong-Hyeok Kim2
1Division of Cardiology, Department of Internal Medicine, Ewha Womans University Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Korea. icho@ewha.ac.kr.
Journal of cardiovascular imaging
|October 30, 2023
概括
厚厚的围脂肪与心力衰竭患者的功能下降有关. 测量这种脂肪可能有助于识别那些患脏问题的风险较高的人.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 放射学 放射学是指放射学
背景情况:
- 心脏功能的急性恶化往往导致功能障碍.
- 患有急性不补偿性心力衰竭和减少喷射率 (HFrEF) 的患者特别容易受到伤害.
- 识别HFrEF中功能障碍的预测因素对于及时干预至关重要.
研究的目的:
- 确定与急性失补偿HFrEF住院患者功能受损相关的临床和成像参数.
- 在这个人群中评估围脂肪厚度和功能之间的关联.
主要方法:
- 分析了来自131名急性失补偿HFrEF (左心室喷射分数<40%) 的住院患者的数据.
- 在入院时按膜过率 (GFR) 分类的患者:保持 (≥60毫升/分钟/1.73米2) 与减少 (<60毫升/分钟/1.73米2).
- 通过计算机断层扫描评估心声回声学参数和围脂肪厚度.
主要成果:
- 60名患者 (46%) 的功能下降.
- 增加的年龄,升高的log N-终端pro b型尿素和增加的周围脂肪厚度独立地与降低的功能有关.
- 围脂肪厚度切线> 12毫米显示了55%的灵敏度和83%的特异性来预测功能障碍.
结论:
- 增加周围脂肪厚度是急性脱补偿HFrEF住院患者功能受损的独立预测因子.
- 围脂肪厚度测量可以作为一个有价值的成像生物标志物.
- 这种标记可以帮助识别患有功能障碍的高风险HFrEF患者.
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