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在HRAS突变型偏瘤中调节上腺素生物合成

Minghao Li1,2, Susan Richter3, Hermine Mohr4

  • 1Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse, Dresden, Germany.

Endocrine-related cancer
|October 30, 2023
PubMed
概括

哈维大鼠肉瘤病毒性瘤基因同源 (HRAS) 突变的帕拉甘瘤 (PGLs) 独立于位置产生上腺素. 这通过基因激活蛋白激酶 (MAPK) 信号传递发生,该信号调节乙醇胺N-甲基转移酶 (PNMT) 表达的表达.

关键词:
在MAPK路径中.类甲基胺 (Catecholamines) 是一种类甲基胺.葡萄糖皮质类药物是什么帕拉格里奥马马是什么意思现型基因型相关性 相关性

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