相关实验视频

Updated: Jul 12, 2025

Legionella pneumophila Outer Membrane Vesicles: Isolation and Analysis of Their Pro-inflammatory Potential on Macrophages

Legionella pneumophila Outer Membrane Vesicles: Isolation and Analysis of Their Pro-inflammatory Potential on Macrophages

Published on: February 22, 2017

作为一个呼吸道病原体的Lophomonas跳过枪的枪

Abhishek Mewara¹, Gillian H Gile², Blaine Mathison^3,4

¹Department of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Journal of clinical microbiology

|October 30, 2023

概括

关于人类Lophomonas感染的报道可能是错误地识别了状上皮细胞,而不是真正的病原体. 目前的诊断方法缺乏特异性,临床证据不足以支持Lophomonas作为人类病原体.

科学领域:

微生物学微生物学
传染性疾病传染性疾病
医学寄生虫学医学寄生虫学

背景情况:

在过去的三十年中,人类感染原生动物Lophomonas的报道有所增加.
最初的诊断依赖于显微镜识别,在Lophomonas blattarum的聚合酶链反应 (PCR) 开发后,报告的数量急剧增加.

研究的目的:

评估Lophomonas作为人类病原体的潜在作用.
批判性地评估有关人类Lophomonas感染的已发表证据.

主要方法:

从人类标本中分析了所谓的Lophomonas的已公布图像和视频.
与宿主支气管纤维状上皮细胞和真正的L. blattarum. 的形态学和运动性的比较.
对诊断PCR方法和报告病例的临床数据的审查.

主要成果:

来自人类标本的图像和视频主要显示错误识别的状上皮细胞,而不是真正的Lophomonas.
临床证据不足;表现是非特异性的,缺乏可归因的组织病理.
已发表的PCR测定没有特异性,并且可以放大来自共生三种类的DNA.

结论:

根据目前的证据,Lophomonas不太可能是人类的重要病原体.
在将微生物归类为新型人类病原体之前,严格的科学审查是必不可少的.
错误诊断对患者的护理和科学文献的完整性构成风险.

关键词:

洛福蒙纳斯 (Lophomonas) 是一个人.西里亚西里亚是什么意思状细胞光症 (ciliocytophthoria) 是一种标记为旗的地区.错误的识别和错误的识别寄生虫是一种寄生虫.

更多相关视频

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip

Author Spotlight: Advancing Rapid Detection of Respiratory Pathogens Using Microfluidic Chip

Published on: March 29, 2024

相关概念视频

Pneumonia II: Pathophysiology

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:

Pneumonia I: Introduction

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...

Defense Against Bacterial Pathogens

Defense Against Bacterial Pathogens

The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...

Bacterial Phylum Spirochaetes

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...

Common Respiratory Disorders

Common Respiratory Disorders

Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...

Bacterial Phylum Proteobacteria

Bacterial Phylum Proteobacteria

Proteobacteria, one of the largest and most diverse bacterial phyla, encompasses a wide range of Gram-negative bacteria distinguished by their outer membrane composed of lipopolysaccharides. These microorganisms exhibit various metabolic capabilities, including phototrophy, chemolithotrophy, and heterotrophy, and thrive in diverse environments from soil to aquatic systems and host-associated niches. The phylum is divided into six classes: Alphaproteobacteria, Betaproteobacteria,...