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Tracking Bispecific Antibody-Induced T Cell Trafficking Using Luciferase-Transduced Human T Cells
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依赖T细胞的双特异性疗法增强了先天性免疫激活和抗体介导的杀死

Rickvinder Besla1, Elicia Penuel1, Geoff Del Rosario1

  • 1Genentech Research and Early Development, Genentech Inc., South San Francisco, California.

Cancer immunology research
|October 30, 2023
PubMed
概括

依赖T细胞的双特异性抗体 (TDB) 激活自然杀手 (NK) 细胞和巨细胞,增强它们杀癌的能力. 这项研究揭示了TDB如何利用先天免疫力,为血液和固体瘤提出了新的组合疗法.

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