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Updated: Jul 12, 2025

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通过不同的受体相互作用模式,Cbl和Cbl-b独立调节EGFR

Itziar Pinilla-Macua1, Alexander Sorkin1

  • 1Department of Cell Biology, University of Pittsburgh, School of Medicine, Pittsburgh, PA, 15261.

Molecular biology of the cell
|October 30, 2023
PubMed
概括

Cbl和Cbl-b E3酶控制了EGF受体 (EGFR) 的无化和降解. 这项研究表明,它们通过不同的EGFR结合机制独立运作,影响细胞迁移.

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