计算机断层扫描在大动脉狭窄中的分:双与三形态:双与三形态
Zi Ye1, Marie-Annick Clavel2, Thomas A Foley3
1Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Heart (British Cardiac Society)
|October 30, 2023
概括
大动脉的分数在双大动脉 (BAV) 男人和三大动脉 (TAV) 男人和严重的大动脉狭窄 (AS) 之间有所不同. 目前的指导方针可能需要对BAV男性进行调整,因为化程度较高.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 医疗成像医学成像
背景情况:
- 目前的指导方针建议对大动脉的分数 (AVC分数) 和密度 (AVC密度) 进行特定的值,以评估三大动脉 (TAV) 患者的大动脉狭窄 (AS) 的严重程度.
- 双主动脉 (BAV) 形态是一种常见的先天性心脏缺陷,与TAV相比,它可以导致较早和更严重的AS.
研究的目的:
- 为了比较AVC分数和AVC密度在BAV与TAV的患者中.
- 为了确定当前的AS严重性评估值是否适用于BAV患者.
主要方法:
- 对1957名患有心声学AS严重程度和CT-AVC评估的患者进行了回顾性研究.
- 严重的AS根据既定的大动脉面积和血液动力学标准来定义.
- 使用Agatston方法评估的AVC.
主要成果:
- BAV形态与更高的AVC分数和AVC密度有关,特别是在男性中,独立于AS严重程度.
- 在严重的AS中,BAV男性的AVC分数和AVC密度明显高于TAV男性 (p<0.001).
- 在BAV男性 (2916AU和600AU/cm2) 中,严重AS诊断的门高于指导方针建议,而BAV女性的门类似.
结论:
- 在AS中膜化因大动脉形态和性别而有显著的变化.
- 与TAV男性相比,患有严重AS的BAV男性显示出更高的AVC分数和AVC密度,这对当前的指南构成了诊断挑战.
- 需要对更大的队列进行进一步的研究来验证这些发现,并可能修订BAV患者的AS评估指南.
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