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Updated: Jul 12, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells

Published on: October 27, 2020

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塔林-1抑制了Smurf1-介导的Stat3降解,以调节小鼠中的β细胞增殖和质量

Xiaoting Hou1, Yangshan Chen1, Bo Zhou1

  • 1Department of Biochemistry, School of Medicine, Southern University of Science and Technology, Key University Laboratory of Metabolism and Health of Guangdong, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Southern University of Science and Technology, Shenzhen, 518055, China.

Cell death & disease
|October 31, 2023
PubMed
概括

胰腺β细胞中的Talin-1缺乏减少了它们的质量和胰岛素的表达,导致葡萄糖不耐受. 这种蛋白质对于维持β细胞质量至关重要,可能是糖尿病治疗的治疗点.

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