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Updated: Jul 12, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

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对含有α5亚单元的GABAA受体药物选择性的分子基础

Vikram Babu Kasaragod1,2, Tomas Malinauskas3, Ayla A Wahid1

  • 1Department of Pharmacology, University of Cambridge, Cambridge, UK.

Nature structural & molecular biology
|October 31, 2023
PubMed
概括

药物的结构与含有α5亚单元的GABAA受体结合,揭示了选择性药物设计的分子细节. 这项研究促进了对神经系统疾病的正负基调节剂的理解.

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