DC/TMD轴I亚型:东亚TMD患者的世代和性别差异
Adrian Ujin Yap1,2,3, Chengge Liu1,4,5, Jie Lei1,4,5
1Center for TMD & Orofacial Pain, Department of Oral & Maxillofacial Radiology, Peking University School & Hospital of Stomatology, No. 22 Zhong Guan Cun South Ave, Beijing, 100081, China.
BMC oral health
|October 31, 2023
概括
代际和性别差异影响东亚人群中关节障碍 (TMD) 诊断. 了解这些区别对于量身定制的患者护理和未来的TMD研究至关重要.
科学领域:
- 口腔和牙和面部医学
- 牙科公共卫生 牙科公共卫生
- 流行病学 流行病学
背景情况:
- 关节疾病 (TMD) 是一组复杂的疾病,影响关节和肌.
- 现有的TMD研究往往缺乏对世代和性别特异性变异的详细分析,特别是在多样化的种族人口中.
- 关节疾病的诊断标准 (DC/TMD) 为关节疾病的评估提供了一个标准化的框架.
研究的目的:
- 调查东亚患者中关节疾病诊断标准 (DC/TMD) 亚型的患病率的世代和性别差异.
- 确定特定的TMD亚型,这些亚型在不同世代 (X,Y,Z世代) 和性别之间显示出显著的变化.
- 通过突出TMD中的这些人口区别,为临床实践和未来的研究提供信息.
主要方法:
- 来自中国和韩国的1717名首次诊断TMD患者的队列使用DC/TMD方法进行了评估.
- 患者被分为三个世代队列 (X,Y,Z世代) 和按性别进行分类.
- 统计分析,包括奇平方,克鲁斯卡尔-瓦利斯和后勤回归,用于评估TMD诊断中的世代性别差异.
主要成果:
- 在关节痛,肌痛痛,头痛 (Gen X ≥ Y > Z) 和椎间盘位移 (Gen Z > Y > X) 的患病率中观察到显著的代际差异.
- 与老一代相比,Z一代表现出较少的与疼痛相关的TMD和更多的关节内疾病.
- 妇女患上退行性关节疾病和关节内疾病的频率高于男性. 在X世代女性中,疼痛性TMD的风险增加.
结论:
- 在东亚人口中,DC/TMD亚型的呈现存在明显的世代和性别差异.
- 这些人口差异是显著的,在TMD的临床管理中需要考虑.
- 进一步的研究应该探索导致TMD中这些观察到的世代性别差异的潜在因素.
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