使用CMR特征追踪对糖尿病患者的左心房合和左心房功能损害的评估,有或没有高血压
Rui Shi1, Yi-Ning Jiang1, Wen-Lei Qian1
1Department of Radiology, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, Sichuan, China.
Cardiovascular diabetology
|October 31, 2023
概括
高血压会恶化左心房功能,并改变糖尿病患者心房合. 这项研究强调了共同发生的疾病如何影响心脏健康,强调了全面管理的必要性.
科学领域:
- 心脏病学 心脏病学
- 糖尿病学 糖尿病学
- 高血压研究 高血压研究
背景情况:
- 糖尿病 (DM) 和高血压是普遍存在的并发症.
- 这两种情况都与心血管并发症有关.
- 对左心房 (LA) 功能和心房合的综合影响尚未完全理解.
研究的目的:
- 评估同时发生的糖尿病 (DM) 和高血压对左心室 (LA) 功能和左心室合指数 (LACI) 的影响.
- 为了比较DM加高血压 (DM+HP) 与仅DM (DM-HP) 的患者的这些影响.
主要方法:
- 心脏磁共振 (CMR) 用于评估176名DM患者.
- 患者被分为DM+HP (n=103) 和DM-HP (n=73) 组.
- 评估的参数包括LA储,管道和助推功能,LA体积指数 (LAVI),LV全球纵向应变 (LVGLS) 和LACI.
主要成果:
- 与DM-HP组相比,DM+HP组的总LAEF和活性LAEF显著降低.
- 患有DM+HP的患者表现出减少的LA储 (εs),管道 (εe) 和助推器 (εa) 菌株,以及增加的LACI.
- 多变量分析表明高血压独立导致DM患者的LA提升菌株 (εa) 降低和LACI增加.
结论:
- 高血压加剧了LA助推菌株的下降,并增加了DM患者的LACI.
- 在DM患者中,LV GLS与LA阶段性菌株有显著的关联.
- 这些发现表明,由于DM和高血压的联合存在,心房合的潜在变化.
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