心肌弹性成像与在人类循环素诱导心脏毒性模型中的组织病理学相关
Caroline E Miller1,2, Jennifer H Jordan3,4, Alexandra Thomas5,6
1Wake Forest School of Medicine, Biomedical Engineering.
bioRxiv : the preprint server for biology
|October 31, 2023
概括
心肌弹性变化可以预测早期的心脏衰退. 一种新型成像方法 (BEIM) 显示出从化疗中检测心脏毒性的前景,为心脏病提供了敏感的生物标志物.
科学领域:
- 心脏病学 心脏病学
- 生物医学工程 生物医学工程
- 在瘤学瘤学.
背景情况:
- 亚临床心脏衰退检测对于预防心力衰竭至关重要.
- 心肌弹性变化可能作为心脏衰退的早期生物标志物.
- 心脏瘤学在早期检测心脏毒性的治疗中面临挑战,比如人类循环药.
结论:
- 由BEIM衍生出的LV弹性与多克索鲁比的组织病理变化相关.
- 这种方法为评估心脏损伤提供了一个有前途的非侵入性工具.
- LV弹性可以作为心脏毒性和心脏病检测的敏感生物标志物.
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