婴儿时期的伊索尼亚齐德预防治疗不会对暴露于艾滋病毒的未感染儿童的生长产生不利影响:随机对照试验数据的二次分析
Ashenafi S Cherkos1, Sylvia M LaCourse2,3,4, Daniel A Enquobahrie2
1Biostatistics and Epidemiology Department, School of Public Health, University of North Texas Health Science Center, Fort Worth, Texas, USA.
伊索尼亚齐德预防疗法 (IPT) 没有影响长期婴儿成长在艾滋病毒暴露,未感染的婴儿. 这种结核病预防策略在两年内没有显著影响体重与年龄或身高与年龄的z-score.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 已知伊索尼亚预防疗法 (IPT) 可以降低结核病 (TB) 的风险.
- 对婴儿生长的IPT的长期影响,特别是对HIV暴露但未感染 (HEU) 婴儿的长期影响,仍然在很大程度上未知.
- 这项研究研究了IPT对高危人群中婴儿生长轨迹的影响.
结论:
- 对暴露于艾滋病毒的未感染婴儿进行的异化预防疗法 (IPT) 在生命的头两年没有显著影响其生长.
- 这些发现表明,在不影响关键增长指标的情况下,IPT可以安全地用于这一群体.
- 进一步的研究可能会探索与HEU婴儿IPT相关的其他长期健康结果.
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