脑下神经元与后部骨皮层的尖峰相合预测了语音声音的准确性
bioRxiv : the preprint server for biology
|October 31, 2023
概括
脑下细胞核 (STN) 在发言过程中与皮质区域协调. 这种互动的延迟与语音声音错误相关,突出STNN.
科学领域:
- 神经科学是一个神经科学.
- 语音科学 语言科学
- 计算神经科学是一种神经科学.
背景情况:
- 皮质 - 基底腺相互作用对人类行为至关重要,但直接记录是具有挑战性的.
- 甲状腺下核 (STN) 在运动控制和认知功能中发挥作用.
- 要了解STN在语音产生中的作用,需要研究它与皮质区域的动态相互作用.
研究的目的:
- 调查在人类演讲过程中STN和皮质区域之间的直接电生理相互作用.
- 确定STN-皮质合的时间动态及其与语音准确性的关系.
- 探索STN-皮质振荡活动在语音规划和制作中的功能意义.
主要方法:
- 在神经外科患者中,从皮质区域并发电皮质图 (ECoG) 和STN的单单元记录.
- 在自愿的音节重复任务中记录.
- 分析STN神经元和皮质甲-α振荡之间的尖峰相合 (SPC).
主要成果:
- 单个STN神经元表现出与多个皮层区域的短暂尖峰相合 (SPC).
- 在发言过程中,STN神经元的时间与后部上边缘环和上环中的-α振荡同步.
- 延迟的STN-皮质相互作用与增加的语音声音错误有关.
结论:
- STN参与了语音规划和听觉-感觉-运动集成,以准确地表示语音.
- 暂时的STN-皮质合支持高保真性语音生成.
- 单独的射击速率模型不足以解释基底腺节电路功能在语言中.
相关概念视频
01:15Auditory Pathway
5.4K
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
5.4K
01:31Hearing
52.4K
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
52.4K
01:13The Cochlea
45.1K
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
45.1K