辐射前列炎与复发的胃肠道出血,并由细胞巨乳病毒复杂化
Austin B Auyeung1, Melanie N Rayan1, Xiaolan Tang1
1University of Central Florida College of Medicine, Graduate Medical Education/HCA Florida North Florida Hospital, Internal Medicine Residency Program, Gainesville, FL, USA.
The journal of the Royal College of Physicians of Edinburgh
|October 31, 2023
概括
细胞巨乳病毒 (CMV) 的重新激活在前列腺辐射后的免疫能力强的患者中引起严重的胃肠道出血. 这一案例凸显了CMV大肠炎和直肠作为癌症治疗后的潜在并发症.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 在瘤学瘤学.
背景情况:
- 细胞巨乳病毒 (CMV) 感染在免疫能力良好的人群中通常是轻微的,但在免疫功能低下的患者中可能是严重的.
- 毛细菌病毒建立了终身潜伏的初始感染后感染,并有可能重新激活.
- 放射性前列腺炎是前列腺辐射的并发症,可能导致胃肠道出血.
研究的目的:
- 报告CMV引起的免疫能力不佳患者中首例危及生命的胃肠道出血病例.
- 调查CMV感染在前列腺癌放射治疗后不愈合的直肠和结肠炎中的作用.
主要方法:
- 一个81岁的免疫能力强的男性的病例报告.
- 复发性,危及生命的胃肠道出血的临床表现.
- 诊断工作,包括在直肠和结肠活检中识别CMV.
- 对促成因素的审查,包括前列腺辐射,输血和CMV感染.
主要成果:
- 患者经历了多次严重的胃肠道出血.
- 一个不愈合的直肠检测出CMV和CMV结肠炎的阳性被确定为出血的来源.
- 该患者具有免疫能力,挑战了对严重的CMV表现的典型理解.
结论:
- 重新激活的CMV可以导致严重的,危及生命的胃肠道出血,即使在免疫能力强的个体.
- 前列腺放射治疗与CMV感染相结合,可能导致复杂的胃肠道并发症,如CMV大肠炎和不愈合的.
- 复发性出血事件可能是多因素的,涉及前列腺辐射,CMV感染和潜在的输血.
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