在津巴布韦城市地区的关键人群中,PrEP保留预测因素 - - 一种机器学习方法
Bridgette Bero1, Chipo Zidana2, Sarudzai Portia Showa1
1Department of Applied Mathematics, National University of Science and Technology, Bulawayo, Zimbabwe.
African journal of AIDS research : AJAR
|October 31, 2023
概括
了解影响暴露前预防 (PrEP) 保留的因素是预防艾滋病毒的关键. 女性性工作者和某些成年人群体表现出更好的prep坚持,突出了定制的保留策略.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 预防艾滋病毒 预防艾滋病毒
背景情况:
- 暴露前预防 (PrEP) 是一种关键的艾滋病毒预防工具.
- 成功实施PrEP在很大程度上取决于持续的坚持和在护理中保持.
- 确定影响PrEP保留的因素对于优化其有效性至关重要.
研究的目的:
- 确定影响PREP在六个月后保留时间的关键因素.
- 根据保留模式,识别PrEP用户的不同群体.
主要方法:
- 利用了在津巴布韦2017-2019年期间开始使用PrEP的个人数据.
- 采用多变量后勤回归来确定保留决定因素.
- 应用了围绕 medoids (PAM) 的分区集群分析来定义保留集群.
主要成果:
- 保持PrEP的重要决定因素包括人口类型,性别,婚姻状况,就业,年龄和教育.
- 女性性工作者在保持PrEP的可能性最高.
- 确定了三个不同的风险集群:已婚高风险成年男性 (32%的保留率),与男性发生性关系的年轻单身男性 (MSM) (24%的保留率) 和分居/离婚的成年女性性工作者 (44%的保留率).
结论:
- 成年人,女性性工作者,高风险人群,女性和教育程度较低的人群表现出更好的prep保留率.
- 年轻人,MSM,男性,以及拥有高等教育或就业的个人,其保留率较低.
- 研究结果强调,需要针对性干预措施,以改善PrEP在不同人群中的保留率.
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