术前骨质疏松症作为老年患者胃切除术后因其他疾病死亡的危险因素
Shota Shimizu1, Tomoyuki Matsunaga2, Y U Sakano2
1Division of Gastrointestinal and Pediatric Surgery, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine, Yonago, Japan s.shimizu@tottori-u.ac.jp.
In vivo (Athens, Greece)
|October 31, 2023
概括
手术前的骨质疏松症,即低骨密度的度量,与老年胃癌患者的非癌症死亡率增加有关. 这一发现强调了评估胃癌手术的老年人骨健康的重要性.
科学领域:
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
- 放射学 放射学是一门学科.
背景情况:
- 手术前的骨质疏松症是消化道癌症的已知预后因素.
- 老年患者骨质疏松症和胃癌 (GC) 之间的具体关系尚不清楚.
研究的目的:
- 调查术前骨质疏松症与胃腺癌的老年患者的结果之间的相关性.
- 为了确定手术后老年GC患者死亡的风险因素.
主要方法:
- 分析了251名胃腺癌患者的队列,这些患者接受了治疗性手术.
- 患者被分为非老年人 (n=169) 和老年人 (n=82) 组.
- 骨矿物质密度使用手术前计算机断层扫描 (CT) 和霍恩斯菲尔德单位进行评估.
主要成果:
- 老年患者的骨质疏松率显著高,预后营养指数 (PNI) 较低.
- 虽然老年人的整体存活时间较短,但疾病特异性存活率没有显著差异.
- 多变量分析确定了手术前骨质疏松症和低PNI作为老年人胃切除术后非癌症死亡的显著风险因素.
结论:
- 手术前的骨质疏松症是影响胃癌老年患者治愈能力和非癌症死亡率的关键因素.
- 在手术前评估骨矿物质密度和营养状况对于管理老年GC患者至关重要.
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