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Production and Visualization of Bacterial Spheroplasts and Protoplasts to Characterize Antimicrobial Peptide Localization
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来自粗粒度模拟的微生物抗菌小化的机制

Ezequiel N Frigini1,2, Rodolfo D Porasso3, Tamás Beke-Somfai4

  • 1Facultad de Química, Bioquímica y Farmacia, Instituto Multidisciplinario de Investigaciones Biológicas (IMIBIO-SL), Universidad Nacional de San Luis, Ejército de los Andes 950, San Luis 5700, Argentina.

Journal of chemical information and modeling
|October 31, 2023
PubMed
概括

短抗微生物 (AMP) 是有前途的治疗方法. 分子动力学模拟显示它们的膜破坏机制涉及诱导机械应力和破裂,指导未来的药物设计.

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Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
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