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Updated: Jul 12, 2025

High Throughput In Vitro Assessment of Latency Reversing Agents on HIV Transcription and Splicing
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艾滋病毒-1 Tat 通过控制 hnRNPA2 介导的拼接来控制 Rev-viral RNA 复合物的核出口

Sriram Yandrapally1, Satarupa Sarkar1, Sharmistha Banerjee1

  • 1Department of Biochemistry, School of Life Sciences, University of Hyderabad , Hyderabad, Telangana, India.

Journal of virology
|October 31, 2023
PubMed
概括

人类免疫缺陷病毒 (HIV) 使用HIV-1 Tat蛋白调节宿主细胞因子,增加CD4+ T淋巴细胞中的病毒复制,但不是星体细胞. 这解释了HIV在不同细胞类型中的差异性扩散和持久性.

关键词:
艾滋病毒 艾滋病毒 艾滋病毒 Rev Rev艾滋病毒 艾滋病毒 艾滋病毒 Tat HIV Tat通过RNA拼接进行RNA拼接.复杂的Rev-RNA复合体是什么替代性拼接是一种替代性的拼接.不同质的核核核糖核蛋白蛋白质.核细胞质人口贩运 核细胞质人口贩运

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