系统综述和元分析:食物,饮料和饮食及其对成年人慢性便秘的影响
Alice Van Der Schoot1, Zoi Katsirma1, Kevin Whelan1
1Department of Nutritional Sciences, King's College London, London, UK.
Alimentary pharmacology & therapeutics
|October 31, 2023
概括
像水果和麦面包这样的饮食干预措施显示出改善便秘的希望. 然而,由于对各种食物,饮料和慢性便秘管理饮食的证据有限,需要更多的研究.
科学领域:
- 胃肠病学和营养科学 胃肠病学和营养科学
- 临床研究和证据综合
背景情况:
- 饮食方法被认为是治疗慢性便秘的有效方法.
- 缺乏对特定食物,饮料和饮食对便秘的影响的系统审查和元分析.
研究的目的:
- 系统地审查和分析食物,饮料和饮食对治疗反应,便产量,肠道过渡时间,症状,生活质量,不良事件和慢性便秘的成年人遵守的影响.
主要方法:
- 通过电子数据库识别的干预试验 (RCT,非随机,不受控制) 的系统审查和元分析,截至2023年7月12日.
- 使用Cochrane 2.0或JBI批判性评估评估的偏差风险.
- 使用随机效应模型 (风险比率,平均差异,标准化平均差异与95% CI) 合成的RCT数据.
主要成果:
- 包括23项研究 (17项RCT,6项不受控制;1714名参与者),检查了各种干预措施,如果,高矿物质水,,麦面包和不同的饮食.
- 果实,特别是,与相比,便频率增加 (MD: +0.36 BM/周).
- 与白面包相比,面包增加了便频率 (MD:+0.43 BM/周),高矿物质水改善了治疗反应 (RR: 1.47).
结论:
- 水果和麦面包可能为特定的便秘相关结果提供好处.
- 关于各种食物,饮料和饮食对便秘的疗效的高质量证据非常稀缺.
- 进一步的随机对照试验对于建立慢性便秘的最终饮食建议至关重要.
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