交配设计对植物育种种群的附加遗传变异的影响
Tobias Lanzl1, Albrecht E Melchinger1,2, Chris-Carolin Schön3
1Plant Breeding, TUM School of Life Sciences, Technical University of Munich, 85354, Freising, Germany.
概括
交配设计显著影响附加遗传差异估计,影响遗传收益的预测. 仔细选择交配策略和统计方法对于准确评估繁殖种群中的遗传差异至关重要.
科学领域:
- 量化遗传学 量化遗传学
- 动物和植物育种 动物和植物育种
背景情况:
- 添加性遗传变异是预测种群遗传收益的关键.
- 增加性遗传变异的估计受遗传结构和QTL共变的影响.
研究的目的:
- 开发一个理论框架来计算从基因型数据的附加遗传变异及其组成部分.
- 调查不同交配设计对附加遗传差异估计差异差异的影响.
主要方法:
- 模拟的繁殖群体与不同数量的父母 (2-16).
- 采用了三种交配设计:不连接的,因数的和半拨号的交叉.
- 计算了由基因变异标准化添加基因变异和QTL共变异的变异.
主要成果:
- 由少数不连接的交叉产生的大型双亲家庭的交配设计,由于强大的QTL共差,可能会增加或减低附加的遗传差异估计.
- 一轮重组可以有效地破坏诱导的QTL共变性.
结论:
- 交配设计对实现的附加遗传变异和随后的选择收益预测产生了重大影响.
- 准确估计附加遗传变异需要统计方法,以考虑QTL共变和遗传结构.
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