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Updated: Jul 12, 2025

Non-Invasive Ultrasound Assessment of Endometrial Cancer Progression in Pax8-Directed Deletion of the Tumor Suppressors Arid1a and Pten in Mice
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Published on: February 17, 2023

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在人类子宫内膜癌细胞中,探索由ARID1A突变/淘汰引起的下游分子通路的改变

Baoling Xing1, Xiaoying Zhang2, Xia Gu2

  • 1Department of Pathology, Affiliated Zhoupu Hospital of Shanghai University of Medicine and Health Sciences, Shanghai, 201318, China. 793506861@qq.com.

Journal of cancer research and clinical oncology
|October 31, 2023
PubMed
概括

ARID1A基因突变促进子宫内膜癌 (EC) 的发展. 在EC细胞中淘汰ARID1A增强了增殖和微卫星的不稳定性,这表明ARID1A是潜在的治疗点.

关键词:
富含AT的交互领域1A这就是CRISPR/Cas9的作用.细胞循环的细胞周期这是子宫内膜癌的癌症.微卫星的不稳定性是微观的在PI3K/Akt信号通路中.

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