[与COVID-19相关的儿童多系统炎症综合征 (MIS-C) 的临床表型]
Giancarlo Alvarado-Gamarra1, Olguita Del Aguila1, Jesús Dominguez-Rojas1
1Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú.
Andes pediatrica : revista Chilena de pediatria
|October 31, 2023
概括
与COVID-19相关的儿童多系统炎症综合征 (MIS-C) 呈现出不同的表型. 冲击表型在秘鲁儿童中最常见,这表明需要早期诊断和管理.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 与COVID-19相关的儿童多系统炎症综合征 (MIS-C) 是一种罕见但严重的疾病.
- 关于拉丁美洲MIS-C表型的数据有限.
研究的目的:
- 在秘鲁利马的住院儿童中描述MIS-C的临床表型.
- 分析与不同MIS-C表型相关的临床结果.
主要方法:
- 一项对58名被诊断患有MIS-C.的14岁以下儿童进行的回顾性描述性研究.
- 患者被分为冲击,没有冲击的川崎病 (KD) 和发烧/炎症表型.
- 分析了临床人口统计和微生物学数据.
主要成果:
- 冲击表型是最常见的 (55.2%),其次是没有冲击的KD (25.8%) 和发烧/炎症 (19%).
- 胃肠道和粘膜皮肤症状在所有表型中都是常见的.
- 死亡率为3.5%,冠状动脉瘤发生在10.2%,冲击表型患者的结果更差.
结论:
- 冲击表型是最常见的,并且与秘鲁儿童患有MIS-C.的临床结果较差有关.
- 早期监测和迅速管理MIS-C表型对于改善患者预后至关重要.
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