解读四个饮用水分配系统中不同消毒剂的非结核菌群体的多样性和聚集机制
Jinhao Yang1, Yuxing Hu1, Yue Zhang1
1State Key Laboratory of Pollution Control and Resources Reuse, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China; Shanghai Institute of Pollution Control and Ecological Security, Shanghai 200092, China.
The Science of the total environment
|October 31, 2023
概括
非结核菌 (NTM) 在饮用水系统中存在. 这项研究确定了占主导地位的NTM物种以及消毒剂如何影响它们在水和生物膜中的社区.
科学领域:
- 环境微生物学环境微生物学
- 水质研究 水质研究
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,非结核性真菌菌 (NTM) 感染正在增加.
- 饮用水配送系统 (DWDS) 是NTM的潜在储和传输路径.
- 在DWDS中对NTM的物种级理解是有限的.
研究的目的:
- 为了描绘NTM社区结构和物种层面的丰富性,从四个DWDS中取水和生物膜样本.
- 调查三种消毒剂 (自由,胺,二氧化) 对NTM社区的影响.
- 探索DWDSs中NTM社区的组装机制.
主要方法:
- 使用高通量测序和定量PCR (qPCR) 来分析NTM社区.
- 从四个DWDS采集了水和生物膜样本,使用不同的消毒剂.
- 评估了NTM社区的组成,丰富性和组装过程.
主要成果:
- 菌株Mycobacterium paragordonae和菌株Mycobacterium mucogenicum是NTM的主要物种.
- 菌根和Mycobacterium chelonae的数量很少,但患病率很高.
- 胺在水中选择性地影响了NTM社区,导致了明显的社区分离.
- 生物膜的NTM社区比水更加多样化,不同的物种表现出息地偏好.
- 随机过程在生物膜中主导了NTM社区集会,而随机和决定性过程在水中发挥了作用.
结论:
- 本研究提供了在不同消毒策略下对DWDS中NTM社区动态的全面分析.
- 研究结果强调了消毒剂和环境组件 (生物膜与水) 对NTM的影响.
- 这项研究为饮用水基础设施中NTM的风险评估和管理提供了关键数据.
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