在跑完波士顿马拉松后,胃肠细胞损伤和感知症状
Melani R Kelly1,2, Dawn M Emerson1,3, Brendon P McDermott4
1Department of Health, Sport, and Exercise Sciences, University of Kansas, Lawrence, KS, United States.
Frontiers in physiology
|November 1, 2023
概括
马拉松跑步者经历了显著的胃肠道 (GI) 痛苦和肠道细胞损伤,症状在比赛后达到顶峰. 肠道脂肪酸结合蛋白 (I-FABP) 水平和胃肠道症状与脱水相关,突出了个体风险因素.
科学领域:
- 运动生理学 运动生理学
- 胃肠病学 胃肠病学
- 运动医学 运动医学
背景情况:
- 胃肠道 (GI) 障碍在马拉松运动员中很常见,可能导致热中风等严重疾病.
- 了解运动引起的胃肠道问题背后的机制和风险因素对于运动员的健康至关重要.
研究的目的:
- 为了研究肠道细胞损伤,以肠道脂肪酸结合蛋白 (I-FABP) 测量,以及马拉松跑者感知到的胃肠道症状.
- 为了确定潜在的风险因素,如睡眠不足,可能会在耐力赛期间加剧胃肠道障碍.
主要方法:
- 一个并行的混合方法设计被采用了2019年波士顿马拉松的40名马拉松选手.
- 参与者完成了关于人口统计和训练的赛前调查,GI问卷,并在赛前,赛后和24小时赛后提供尿样. 血液样本是立即和比赛后24小时收集的.
主要成果:
- 肠道脂肪酸结合蛋白 (I-FABP) 水平从比赛后明显下降到比赛后的24小时 (p < .001).
- 整体胃肠道症状得分在时间点之间显示出显著差异,在比赛后立即达到顶峰 (p < .001).
- 赛后的I-FABP和尿液特异性重量与赛后的胃肠道症状严重程度有显著的相关性 (p = .048和p = .041).
结论:
- 马拉松运动员的胃肠道障碍高度个性化,受到一系列风险因素的影响.
- 肠道细胞损伤标志物和感知到的胃肠道症状在马拉松后升高,并且可能与水分状态有关.
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