上大腿骨肌指数预测了肝移植接受者的结果
Manuel Lim1,2, Jong Man Kim1, Jaehun Yang1
1Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Annals of surgical treatment and research
|November 1, 2023
概括
上大腿骨肌指数 (UT-SMI) 有效地诊断肝移植 (LT) 接受者的肉症. 通过UT-SMI识别的肉类与LT后患者和移植的存活率较差有关.
科学领域:
- 医疗成像医学成像
- 肝病学 肝病学是一种肝病学.
- 老年病的医生 老年病的医生
背景情况:
- 萨科佩尼亚诊断通常使用L3骨肌指数 (SMI).
- 上大腿 (UT) 肌肉质量变化反映了全身肌肉,但其在肝移植 (LT) 后诊断肉类症的使用尚未检查.
- 肝移植接受者容易患上肉症,这会影响结果.
研究的目的:
- 确定最佳的上大腿骨肌肉指数 (UT-SMI) 切断值,以诊断LT接受者的肉类症.
- 研究UT-SMI诊断的肉类症与LT后患者/移植存活结果之间的相关性.
主要方法:
- 对332名LT患者 (2018-2020年) 的回顾性分析.
- 计算UT-SMI和确定肉症切线值.
- 多变量考克斯分析,以评估预后因素的生存.
主要成果:
- 最佳的UT-SMI切线:38.3厘米/平方米 (女性) 和46.7厘米/平方米 (男性).
- 按UT-SMI计算的肉类的患病率为33.4%.
- 通过UT-SMI诊断的肉类瘤与患者和移植存活率较差显著相关 (P < 0.001).
结论:
- UT-SMI是一种可行的工具,用于诊断LT接受者的肉症.
- 诊断为UT-SMI的肉是患者和移植存活的独立预后因素.
- UT-SMI提供了一种有价值的基于CT的评估,用于LT人群中 Sarcopenia.
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