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Updated: Jul 12, 2025

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Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
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在接种COVID-19疫苗后,青少年出现两例甲状腺炎病例
Sri Nikhita Chimatapu1, Christopher J Ferber1, Apisadaporn Thambundit1
1Department of Pediatrics, Division of Endocrinology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.
JCEM case reports
|November 1, 2023
概括
这项研究报告说,在接种COVID-19疫苗后,有两例儿童患有Graves病. 儿科医生应在接种疫苗后监测甲状腺炎症状,以确保及时治疗.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 免疫学 免疫学 免疫学
- 疫苗学 疫苗学 疫苗学
背景情况:
- COVID-19疫苗接种活动引起了人们对潜在副作用的担忧.
- 成人病例报告表明,COVID-19疫苗接种和甲状腺炎之间可能存在联系.
研究的目的:
- 描述COVID-19疫苗接种后儿童中首次报告的Graves疾病病例.
- 提高儿科医生对疫苗接种后潜在的甲状腺并发症的认识.
主要方法:
- 一系列病例描述了两个儿科患者.
- 审查了临床表现,实验室发现 (包括甲状腺刺激性免疫球蛋白水平),以及对格雷夫斯病的治疗.
主要成果:
- 两名儿童在接种瑞生物科技COVID-19 mRNA疫苗后出现了甲状腺过活性的症状.
- 这两名患者的甲状腺刺激性免疫球蛋白水平均为阳性,并接受了格雷夫斯病治疗.
结论:
- 这一案例系列表明COVID-19疫苗接种与儿科人口中的Graves病之间存在潜在的关联.
- 儿科医生应在接种疫苗后呈现相关症状的儿童中保持甲状腺炎的高怀疑指数.
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