对状细胞肺癌FGFR1依赖机制的基因组洞察

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Netta Mäkinen1,2, Matthew Meyerson1,2,3

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

The Journal of clinical investigation
|November 1, 2023
PubMed
概括

新的发现揭示了肺状细胞癌 (LSCC) 中FGFR1附近的尾到尾重组. 这些遗传变化预测了对纤维细胞生长因子受体 (FGFR) 抑制剂的敏感性,这可能会改善LSCC患者的向治疗选择.

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