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Updated: Jul 12, 2025

Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death
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Identification of Intracellular Signaling Events Induced in Viable Cells by Interaction with Neighboring Cells Undergoing Apoptotic Cell Death

Published on: December 27, 2016

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双固态mTORC1抑制剂在瘤模型中诱导细胞死亡,mTORC1过度活化

Heng Du1, Yu Chi Yang2, Heng-Jia Liu1

  • 1Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

The Journal of clinical investigation
|November 1, 2023
PubMed
概括

双硬性mTORC1选择性抑制剂在治疗具有mTORC1过活化的癌症方面表现有前途. 这些新型抑制剂有效地降低瘤生长并诱导亡,通过向4EBP1.1,优于现有的Rapalogs.

关键词:
癌症 癌症 癌症 癌症在瘤学瘤学.治疗方法 治疗方法

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