身体活动和运动对Nucleobindin-2基因表达和Nesfatin-1度的影响:快速审查
Saleh Rahmati1,2, Behnam Mohammadi2, Zahra Karimi-Mehr2
1Department of Physical Education, Pardis Branch, Islamic Azad University, Pardis, Iran.
Cell biochemistry and function
|November 1, 2023
概括
身体活动和炼通常会增加人类和动物的核丁-2 (NUCB2) 和纳斯法丁-1水平. 然而,关于急性运动效应和人体活检研究的研究是有限的,需要进一步调查.
科学领域:
- 运动生理学 运动生理学
- 分子生物学分子生物学
- 内分泌学 在内分泌学.
背景情况:
- 核丁-2 (NUCB2) 基因表达及其产物纳斯法-1在能量稳态和食欲调节中发挥作用.
- 了解体育活动对NUCB2/Nesfatin-1的影响对于代谢和肥胖研究至关重要.
研究的目的:
- 系统地审查现有关于身体活动和运动对NUCB2基因表达和Nesfatin-1度的影响的研究.
- 确定有关运动和NUCB2/Nesfatin-1的当前文献中的差距.
主要方法:
- 进行了对五个主要科学数据库 (PubMed,Science Direct,Springer,Wiley,Google Scholar) 的快速审查.
- 包括到2023年8月发表的研究,研究人类和动物对运动的反应.
- 数据合成的重点是NUCB2基因表达和Nesfatin-1度 (组织和血) 的变化.
主要成果:
- 人类研究表明,运动训练通常会增加纳斯法廷-1度,而更高的强度和持续时间可能会突出这一效应.
- 动物研究主要表明,定期运动训练会增加组织NUCB2/Nesfatin-1.
- 对于人类的急性运动反应存在相互矛盾的结果,并注意到缺乏人类活检研究和动物研究的急性运动.
结论:
- 身体训练似乎是增加NUCB2/Nesfatin-1水平在人类和动物中的一个重要因素.
- 目前关于急性运动对NUCB2/Nesfatin-1的影响的研究是初步的.
- 未来的研究应该集中在人体活检研究,急性运动反应和不同训练方案的比较分析上.
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