功能连接在利维体病与视觉幻觉的功能连接性
Michael J Firbank1, Daniel Collerton1, Katrina daSilva Morgan1
1Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
European journal of neurology
|November 1, 2023
概括
在勒维体病 (LBD) 中的视觉幻觉与大脑连接的改变有关. 在经历幻觉的LBD患者中观察到注意力和视觉网络的功能连接性减少.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
背景情况:
- 视觉幻觉是莱维体病 (LBD) 的常见症状之一.
- 这些幻觉的神经支尚未完全理解.
- 之前的模型表明,注意力和视觉处理网络的连接性变化至关重要.
研究的目的:
- 为了研究LBD和视觉幻觉患者的大脑连接差异.
- 探索连接性和认知/运动功能之间的关系.
主要方法:
- 检查了41名LBD和视觉幻觉的个体的功能连接,48名LBD没有幻觉,60名健康对照.
- 研究视觉皮层和注意力/默认模式网络之间的联系.
主要成果:
- 视觉幻觉的个体表现出更差的认知和运动功能.
- 在患有幻觉的人群中,在腹部注意网络和从视觉到默认模式网络中发现功能连接性减少.
- 连接强度与认知任务的表现相关.
结论:
- 这些发现支持了视觉幻觉LBD患者视觉和注意网络功能障碍的证据.
- 突出了网络改变在LBD相关的视觉幻觉中的作用.
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